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Life Extension Magnesium Caps
SCIENTIFIC SCORE
Questionable
Based on 23 Researches
6.6
USERS' SCORE
Good
Based on 13 Reviews
8.3
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Magnesium [as magnesium oxide, citrate, succinate)
500 mg
119%

Top Medical Research Studies

9
Magnesium implantation improves heart recovery
Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats.
Direct effect on MI treatment
We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.

Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.

Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Read More
8
Magnesium levels impact heart attack outcomes
Serum Magnesium Level and It's Relation in Predicting Adverse In-Hospital Outcome in Patients with First Attack of Myocardial Infarction.
Demonstrates important clinical association
We examined whether serum magnesium levels at admission could predict in-hospital outcomes for patients experiencing a heart attack.

In our study of 259 acute myocardial infarction patients, those with lower magnesium levels (below 1.82 mg/dl) faced significantly higher risks of complications, including arrhythmias and even death, compared to those with healthier levels.

Our findings suggest that maintaining adequate magnesium levels is essential for better health outcomes after a heart attack.
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5
OCT and angiography show comparable effectiveness
Optical Coherence Tomography- Versus Angiography-Guided Magnesium Bioresorbable Scaffold Implantation in NSTEMI Patients.
Heart health treatment decision-making.
We examined how two guidance methods—optical coherence tomography (OCT) and angiography—perform during magnesium bioresorbable scaffold (MBRS) implantation in patients recovering from a non-ST-elevation heart attack.

With 75 participants, our study revealed that both techniques resulted in comparable healing patterns after six months. Though OCT-guided intervention showed slightly better outcomes in certain technical measures, neither approach demonstrated a significant advantage in overall heart healing.

Thus, for NSTEMI patients, choosing between OCT and angiography for MBRS placement may depend on other factors, as both methods appear effective.
Read More

Most Useful Reviews

9.5
Reduces heart issues
Life Extension's magnesium supplement is fantastic. It aids in recovery and alleviates stress due to deficiencies. It helps with heart health and lowers blood pressure, enhances energy production, and improves sleep. This supplement also has anti-inflammatory benefits, making it a vital part of my diet.
Read More
9.5
Improved energy
Since starting this magnesium supplement, I feel more energetic and experience less pain overall, including in my heart. I will continue using this supplement and highly recommend it to others for heart health.
Read More
9.5
Pain reduction noted
I bought this due to heart pain and noticed a 90% reduction in pain within two weeks. The quality is high, and it regulates sleep while also offering muscle and joint support. Magnesium is essential for our bodies.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 23 Researches
6.6
  • All Researches
9
Magnesium implantation improves heart recovery
Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats.
Direct effect on MI treatment
We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.

Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.

Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Read More
9
Magnesium scaffolds improve heart attack outcomes
Outcomes of the two generations of bioresorbable scaffolds (Magmaris vs. Absorb) in acute coronary syndrome in routine clinical practice.
Study indicates magnesium benefits
We examined the performance of two types of bioresorbable scaffolds in patients experiencing acute coronary syndrome (ACS) - a common and serious manifestation of heart disease. Specifically, we compared the effectiveness of magnesium-based scaffolds, known as Magmaris, with the earlier polymer scaffolds called Absorb.

Our study included 193 patients using Magmaris and 160 patients using Absorb, all treated in similar clinical settings. Over the course of one year, we monitored their health outcomes, particularly focusing on serious issues like cardiac death, heart attacks, and instances of scaffold thrombosis.

Surprisingly, we found that patients with Magmaris had significantly better outcomes than those with Absorb. Specifically, the rates of primary complications and target lesion failures were notably lower with Magmaris. We noted a concerning trend with Absorb, where patients experienced a higher rate of scaffold thrombosis.

Overall, our findings suggest that magnesium-based scaffolds could provide a safer and more effective option for patients undergoing treatment for heart attacks compared to their polymer counterparts.
Read More
8
Magnesium enhances heart attack recovery
Targeted delivery of black phosphorus nanosheets by ROS responsive complex hydrogel based on angiogenesis and antioxidant promotes myocardial infarction repair.
Addresses magnesium's role in MI
We explored an innovative approach to treating myocardial infarction (MI) by using a special composite hydrogel that incorporates magnesium-modified black phosphorus nanosheets. This treatment aims to address the significant changes in the heart's environment after a heart attack, which are usually detrimental to recovery.

The research involved creating a hydrogel scaffold that allows for the gradual release of these magnesium-enhanced nanosheets directly at the site of the infarct. This is particularly important because sustained release helps to manage oxidative stress and inflammation, both common issues following a heart attack.

We observed that the black phosphorus nanosheets have a high reactivity with reactive oxygen species (ROS), which helps reduce oxidative stress and inflammation in the heart. Additionally, the magnesium contributes to promoting blood vessel growth, or angiogenesis, which is crucial for long-term heart function after an MI.

Overall, the findings of this study suggest that the combination of these elements in the hydrogel can effectively block further damage from the heart attack and improve recovery outcomes, signaling a promising avenue for heart attack treatments in the future.
Read More
8
Magnesium improves heart recovery
Magnesium lithospermate B enhances the potential of human-induced pluripotent stem cell-derived cardiomyocytes for myocardial repair.
Study evaluates magnesium's effects.
In our investigation, we set out to understand how magnesium lithospermate B (MLB) can aid heart repair following a heart attack. We used a mouse model with surgically induced myocardial infarction (MI) and categorized the mice into five groups, including those treated with MLB and human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). By comparing different treatments, we evaluated the heart's recovery over four weeks through echocardiography and histochemical staining.

Our findings revealed that MLB significantly enhances the function of hiPSC-CMs, helping to repair the damaged heart muscle. This improvement happens by boosting the function of endothelial cells—important for blood vessel health—through a specific signaling pathway. Additionally, MLB decreases apoptosis, or cell death, in hiPSC-CMs by activating another pathway, which further supports heart recovery.

Overall, our work underscores the role of MLB in improving heart repair after a heart attack. While it was tested in tandem with hiPSC-CMs, which makes it an interesting combination for treatment strategies, it's clear that the integration of MLB can potentially enhance cardiac recovery mechanisms effectively.
Read More
8
Low magnesium indicates higher mortality
Serum Magnesium Is Associated with Long-Term Survival of Non-ST-Elevation Myocardial Infarction Patients.
Moderate relevance to treatment effects
We explored how serum magnesium levels at the time of hospital admission affect the long-term health of patients experiencing a non-ST-elevation myocardial infarction (NSTEMI). In our analysis of data from over 4,500 patients, we focused on the differences between those with low serum magnesium levels—defined as below 1.9 mg/dL—and those with normal or higher levels.

Our findings indicate that patients with low magnesium levels were older, had more health complications like diabetes and hypertension, and faced a higher long-term risk of mortality. Specifically, we observed that 34% of patients with low magnesium levels died within four years, compared to 22% of those with adequate levels.

Importantly, even after adjusting for factors such as sex, existing health conditions, and interventions received during hospitalization, low serum magnesium levels still correlated with a significantly increased risk of death by 24%. While we revealed that low magnesium levels could be a concerning signal for NSTEMI patients, we did not assess the effects of magnesium treatment directly in this study.

Overall, this research brings to light the potential importance of monitoring magnesium levels in the clinical setting, highlighting how they may relate to long-term outcomes for heart attack patients.
Read More

User Reviews

USERS' SCORE
Good
Based on 13 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Reduces heart issues
Life Extension's magnesium supplement is fantastic. It aids in recovery and alleviates stress due to deficiencies. It helps with heart health and lowers blood pressure, enhances energy production, and improves sleep. This supplement also has anti-inflammatory benefits, making it a vital part of my diet.
Read More
9.5
Improved energy
Since starting this magnesium supplement, I feel more energetic and experience less pain overall, including in my heart. I will continue using this supplement and highly recommend it to others for heart health.
9.5
Pain reduction noted
I bought this due to heart pain and noticed a 90% reduction in pain within two weeks. The quality is high, and it regulates sleep while also offering muscle and joint support. Magnesium is essential for our bodies.
8.8
Pain alleviated
I was suffering from heart pain and constipation, but after the first use, both issues improved. The pain in my heart, back, and bones dissipated, and my sleep improved. I made the decision to buy this product after experiencing side effects from the Covid vaccine and finding recommendations for magnesium supplements.
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8
Cramps relieved
This product has been excellent for my heart health and has alleviated leg cramps. The capsules are of good size and easy to swallow. I’m very satisfied with the benefits, particularly for muscle health, as it also helps me sleep well at night.
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